Web Reference: To write a single object to an Excel .xlsx file it is only necessary to specify a target file name. To write to multiple sheets it is necessary to create an ExcelWriter object with a target file name, and specify a sheet in the file to write to. Dec 10, 2017 · This works for me in pandas 0.24.2 for Python 2 (also worked in 0.19.2 when I tried). Jul 23, 2025 · In this example, below Python code uses the Pandas library to append new data (e.g., {'Name': ['Bob'], 'Age': [28], 'Salary': [55000]}) to an existing Excel file ('excel1.xlsx'). It reads the existing data into a DataFrame, appends the new data, and then saves the combined data back to the original Excel file. Output:
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