Web Reference: Apr 10, 2026 · Mutation, an alteration in the genetic material (the genome) of a cell of a living organism or of a virus that is more or less permanent and that can be transmitted to the cell’s or the virus’s descendants. 2 days ago · A mutation is a change in a DNA sequence. Mutations can result from DNA copying mistakes made during cell division, exposure to ionizing radiation, exposure to chemicals called mutagens, or infection by viruses. In biology, a mutation is an alteration in the nucleic acid sequence of the genome of an organism, virus, or extrachromosomal DNA. [1] . Mutations result from errors during replication, mitosis, meiosis, or damage to DNA, which then may trigger error-prone repair [2] or cause an error during replication (translesion synthesis).
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